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What is the purpose of academic research?

images-2As described on our Projects Page, we are a university-based research team led by Dr. David Relman of the Stanford University School of Medicine. Our goal, as academic researchers, is to generate data, making it freely available in public repositories, so that we and others can use that knowledge to develop new, effective interventions for improving health and treating disease. We invite you to participate as a volunteer in this endeavor!

General overview of our three research projects:

imagesWe aim to identify features of bacterial communities that distinguish states of health from the acute and chronic states of hyposalivation and the subsequent development of dental cavities. Ultimately, we hope these microbial features may serve as diagnostics, therapeutics, or prognostics. We are recruiting healthy adults over the age of 18 for the Understanding Oral Health Study, adults between the ages of 18 and 55 for the Understanding Acute Hyposalivation Study, and adults over the age of 18 who were diagnosed with Sjögren’s Syndrome for the Understanding Chronic Hyposalivation Study.

How can I find out if I’m eligible to participate?

We will ask volunteers to complete a telephone interview (Step 1) and a 2-hour no-cost dental examination at the UCSF School of Dentistry (Step 2) before enrolling eligible subjects (Step 3).  Screening  allows us to evaluate whether interested individuals meet the study inclusion and exclusion criteria.

Why are there so many screening steps?

Since this is a scientific research study, we require that each subject who enrolls in the study meet a specific set of study criteria. This allows us to minimize the random variation in our dataset, and is part of the scientific method. Some of our exclusion criteria were also designed to minimize potential risks to volunteers. Each enrollment step we ask interested individuals to complete will help us evaluate whether they meet our study criteria.

To learn details about participating in each specific study, please visit the following pages: 

    1. Participate in the Oral Health Study
    2. Participate in the Acute Hyposalivation Study
    3. Participate in the Chronic Hyposalivation Study

Thank you for your interest in our research!

Our work would not be possible without you.

nidcr_logoThis not-for-profit research project is funded by a National Institute of Dental and Craniofacial Research grant (R01-DE23113-001) to Dr. David Relman.